Current Issue : April-June Volume : 2022 Issue Number : 2 Articles : 5 Articles
Glucose monitoring and diabetes management go hand in hand. Evolution of glucose monitoring and diagnostic tools was a necessary step in better diagnosis and management of diabetes. With time we have seen improvements in terms of accuracy, time and sample collection. Some of the greatest initial advancements in this field were brought forward by the work of scientists who are sometimes not credited for the extraordinary work they have done. The first sample to be used in terms of glucose detection was urine, after which came blood and interstitial fluid. Development of newer methods of glucose monitoring range from urine sampling to usage of interstitial fluid, with each method being unique in terms of utility....
How we manage T1DM has changed dramatically and significantly over the past 57 years. The information I have detailed below is my perspective on how my family and I monitored and treated my T1DM 57 years ago as we were taught by the amazing nursing staff at Resurrection Hospital. Great strides with T1DM have been made since starvation diets and with the discovery of insulin 100 years ago: the discovery of insulin at the Department of Physiology, University of Toronto, Canada, in 1921-22 was one of the most dramatic events in the history of therapeutics. Insulin’s impact was so exciting and sensational because of the incredible effect it had on Type 1 patients with diabetes-truly a miracle of medicine in the 20th century. Frederick Banting and Charles Best won the Nobel Prize in 1922: “called one of the greatest achievements of modern medicine”....
Diabetes mellitus is one of the most prevalent endocrine disorders associated with macro and micro vascular complications. Lower limb complications associated with diabetes including Diabetic Foot Ulcers (DFU) are a major public health issue worldwide. Novel Coronavirus (COVID-19) is a strain of coronavirus which causes illness in animals and humans. COVID-19 has significantly affected people with chronic medical conditions such as diabetes, hypertension, cardiovascular disease and cancer with severe illness and worse outcomes as well as disruption of their routine medical care provision. We presented a case-study of 59-year-old patient with diabetes and hypertension, with an unexpected DFU complication that resulted in big toe amputation. Therefore it is vital for us as health care professional to find innovative ways to ensure the continuity of medical care/service provision along with the fight of COVID-19....
Introduction: Diabetes is a heterogeneous group of metabolic diseases characterized by chronic hyperglycemia resulting from a defect in the secretion and/or action of insulin, diagnosed by the observation of high levels of glucose in the blood, responsible in the long term for vascular and nervous complications. The diabetic foot is the set of pathological manifestations affecting the foot in relation to the diabetic disease. Approximately 5% of diabetics present a chronic lesion of the foot. Objective: To describe the epidemiological and clinical aspects of the diabetic foot in the medicine/endocrinology department of the Mali hospital. Methodology: This was a retrospective descriptive study from November 2011 to December 2015. It focused on diabetic patients hospitalized in the department with a foot wound and aged 14 years and over. Results: The study involved 94 patients out of 828 hospitalized, a prevalence of 11.35%. Our series included 36 (38.3%) men and 58 (61.7%) women, i.e. a sex ratio of 0.61%. The mean age was 42.66 years with extremes of 14 and 81 years. Type 2 diabetes was present in 95% of the patients with a duration of evolution of more than 5 years in 60.6% of the cases. The mechanism of occurrence of the wounds was minor trauma in 54 cases (57.4%). Self-medication was the primary treatment in 70 patients....................
Background: The outbreak of severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. SARS-CoV-2 has been found to cause multiple organ damage; however, little attention has been paid to the damage to the endocrine system caused by this virus, and the subsequent impact on prognosis. This may be the first research on the hypothalamic-pituitary-thyroid (HPT) axis and prognosis in coronavirus disease 2019 (COVID-19). Methods: In this retrospective observational study, 235 patients were admitted to the hospital with laboratoryconfirmed SARS-CoV-2 infection from 22 January to 17 March 2020. Clinical characteristics, laboratory findings, and treatments were obtained from electronic medical records with standard data collection forms and compared among patients with different thyroid function status. Results: Among 235 patients, 17 (7.23%) had subclinical hypothyroidism, 11 (4.68%) severe non-thyroidal illness syndrome (NTIS), and 23 (9.79%) mild to moderate NTIS. Composite endpoint events of each group, including mortality, admission to the ICU, and using IMV were observed. Compared with normal thyroid function, the hazard ratios (HRs) of composite endpoint events for mild to moderate NTIS, severe NTIS, subclinical hypothyroidism were 27.3 (95% confidence interval [CI] 7.07–105.7), 23.1 (95% CI 5.75–92.8), and 4.04 (95% CI 0.69–23.8) respectively. The multivariate-adjusted HRs for acute cardiac injury among patients with NTF, subclinical hypothyroidism, severe NTIS, and mild to moderate NTIS were 1.00, 1.68 (95% CI 0.56–5.05), 4.68 (95% CI 1.76–12.4), and 2.63 (95% CI 1.09–6.36) respectively....
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